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Abgenix

About Abgenix:

Abgenix develops and commercializes antibody-based therapeutics. Their goal is to create and sustain long-term shareholder value through a diversified strategy that minimizes risk while maximizing opportunity.

Abgenix focuses on delivering high-quality antibodies for a range of disease targets. The company has generated hundreds of these antibodies, several of which are currently in clinical trials. With a successful track record, Abgenix has built a reputation for generating antibodies rapidly, efficiently and cost effectively.



Products:


ABX-EGF and ABX-MA1 -- two antibody product candidates that are being evaluated for potential oncology indications.

ABX-PTH as a potential treatment for secondary hyperparathyroidism (SHPT).

About ABX-EGF (panitumumab)

Abgenix's most advanced antibody product candidate is ABX-EGF (panitumumab), a fully human monoclonal antibody generated using XenoMouse® technology. ABX-EGF targets the epidermal growth factor receptor (EGFr), which is over-expressed in a variety of cancers including lung, breast, bladder, pancreatic, colorectal, kidney and head and neck cancer.

NIH Clinical Trials:

Phase II Drug: ABX-EGFColorectal Cancer MetastasesNIH Link
Phase II Drug: ABX-EGFColorectal Cancer MetastaseNIH Link
Phase IDrug: panitumumab (ABX-EGF) Tumor NIH Link
phase I/PhaseIIDrug: AMG 706Drug: AMG 706NIH Link



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